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VARIANT EFFECT	FUNCTIONAL CLASS	IMPACT
MUTATION TYPE:	CHR: POS:

DBSNP BUILD: EXCLUDE VARIANTS AT VARISNP	READ DEPTH: QUAL:	VARIANTS PER GENE:
SHOW ONLY VARIANTS PRESENT IN COMMON GENES BETWEEN ALL THE INDIVIDUALS SELECTED SHOW ONLY VARIANTS AT EXACTLY SAME POSITION BETWEEN ALL THE INDIVIDUALS SELECTED EXCLUDE ALL VARIANTS PRESENT IN LATEST DBSNP BUILD SHOW ONLY VARIANTS PRESENT AT HGMD

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1000 GENOMES FREQUENCY	EXCLUDE ALL VARIANTS PRESENT IN 1000GENOMES	DBSNP FREQUENCY	EXCLUDE ALL VARIANTS PRESENT IN DBSNP	ESP6500 FREQUENCY	EXCLUDE ALL VARIANTS PRESENT IN EXOME SEQUENCING PROJECT

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CADD	EXCLUDE VARIANTS WITHOUT CADD SCORE	MCAP	EXCLUDE VARIANTS WITHOUT M-CAP SCORE

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Genes:
ACTR8, ACVR1, ADCY10, ALDH4A1, BARD1, CAD, CBLB, CHI3L1, CHI3L2, CHIA, CPOX, DUSP12, EPHA2, GALM, HAAO, HK2, HSPA6, IDH1, IL22RA1, JAK1, LGALS8, MINA, NCF2, NEK2, NEU2, NTRK1, PADI2, PADI4, PCSK9, PNPT1, PPARG, PPT1, PRMT6, RBBP4, STK17B, SULT1C3, THEM5, TNFAIP6, XDH, XYLB,

+ Genes associated with diseases 19

Genes at Omim

ACVR1, ADCY10, ALDH4A1, BARD1, CAD, CHI3L1, CPOX, EPHA2, HAAO, IDH1, NCF2, NEK2, NTRK1, PADI4, PCSK9, PNPT1, PPARG, PPT1, XDH,

ACVR1	Fibrodysplasia ossificans progressiva, 135100 (3)
ADCY10	{Hypercalciuria, absorptive, susceptibility to}, 143870 (3)
ALDH4A1	Hyperprolinemia, type II, 239510 (3)
BARD1	{Breast cancer, susceptibility to}, 114480 (3)
CAD	Epileptic encephalopathy, early infantile, 50, 616457 (3)
CHI3L1	{Schizophrenia, susceptibility to}, 181500 (3) {Asthma-related traits, susceptibility to, 7}, 611960 (3)
CPOX	Coproporphyria, 121300 (3) Harderoporphyria, 121300 (3)
EPHA2	Cataract 6, multiple types, 116600 (3)
HAAO	Vertebral, cardiac, renal, and limb defects syndrome 1, 617660 (3)
IDH1	{Glioma, susceptibility to, somatic}, 137800 (3)
NCF2	Chronic granulomatous disease due to deficiency of NCF-2, 233710 (3)
NEK2	?Retinitis pigmentosa 67, 615565 (3)
NTRK1	Insensitivity to pain, congenital, with anhidrosis, 256800 (3) Medullary thyroid carcinoma, familial, 155240 (3)
PADI4	{Rheumatoid arthritis, susceptibility to}, 180300 (3)
PCSK9	{Low density lipoprotein cholesterol level QTL 1}, 603776 (3) Hypercholesterolemia, familial, 3, 603776 (3)
PNPT1	Combined oxidative phosphorylation deficiency 13, 614932 (3) Deafness, autosomal recessive 70, 614934 (3)
PPARG	{Diabetes, type 2}, 125853 (3) Carotid intimal medial thickness 1, 609338 (3) Insulin resistance, severe, digenic, 604367 (3) Lipodystrophy, familial partial, type 3, 604367 (3) Obesity, severe, 601665 (3) [Obesity, resistance to] (3)
PPT1	Ceroid lipofuscinosis, neuronal, 1, 256730 (3)
XDH	Xanthinuria, type I, 278300 (3)

Genes at Clinical Genomics Database

ACVR1, ALDH4A1, BARD1, CAD, CPOX, EPHA2, NCF2, NEK2, NTRK1, PCSK9, PNPT1, PPARG, PPT1, XDH,

ACVR1	Fibrodysplasia ossificans progressiva
ALDH4A1	Hyperprolinemia, type II
BARD1	Breast cancer, susceptibility to
CAD	Congenital disorder of glycosylation, type Iz
CPOX	Coproporphyria Harderoporphyria
EPHA2	Cataract 6, multiple types
NCF2	Chronic granulomatous disease, autosomal recessive, cytochrome b-positive, type II
NEK2	Retinitis pigmentosa 67
NTRK1	Insensitivity to pain, congenital, with anhidrosis
PCSK9	Hypercholesterolemia, familial, 3
PNPT1	Deafness, autosomal recessive 70
PPARG	Lipodystrophy, familial, partial, type 3 Insulin resistance, severe, digenic
PPT1	Ceroid lipofuscinosis, neuronal, 1
XDH	Xanthinuria, type I

Genes at HGMD

Summary

Number of Variants: 50
Number of Genes: 40

Export to: CSV

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ACTR8
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	3	rs4687757 dbSNP Clinvar	53906513	2597.03	G	A	PASS	1/1	90	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.69030	0.69030	0.48293				None None	None None None None	ACTR8\|0.331819735\|25.35%
ACVR1
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	2	rs1146031 dbSNP Clinvar	158626980	1995.03	C	T	PASS	1/1	75	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.91394	0.91390	0.08850				None None	None None None None	ACVR1\|0.908763541\|3.27%
ADCY10
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	1	rs203849 dbSNP Clinvar	167849414	748.6	A	G	PASS	0/1	56	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.49321	0.49320	0.46570				None None	None None None None	ADCY10\|0.02878338\|70.03%
ALDH4A1
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	1	rs7550938 dbSNP Clinvar	19202917	2415.6	T	C	PASS	0/1	160	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.66094	0.66090	0.37698				None None	None None None None	ALDH4A1\|0.121498662\|47.22%
	View	wt108005 snp	1	rs2230708 dbSNP Clinvar	19201956	1608.6	A	G	PASS	0/1	157	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.73722	0.73720	0.29779				None None	None None None None	ALDH4A1\|0.121498662\|47.22%
BARD1
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	2	rs2070093 dbSNP Clinvar	215632256	2457.03	A	G	PASS	1/1	83	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.77057	0.77060	0.28618				None None	None None None None	BARD1\|0.230178617\|33.35%
CAD
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	2	rs3739092 dbSNP Clinvar	27462076	1611.6	C	T	PASS	0/1	131	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.26558	0.26560	0.23405				None None	None None None None	CAD\|0.237806166\|32.61%
	View	wt108005 snp	2	rs1141313 dbSNP Clinvar	27460968	921.6	A	G	PASS	0/1	108	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.45467	0.45470	0.44987				None None	None None None None	CAD\|0.237806166\|32.61%
CBLB
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	3	rs2305035 dbSNP Clinvar	105439026	1028.6	G	A	PASS	0/1	79	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.21006	0.21010	0.20429				None None	None None None None	CBLB\|0.559095691\|13.39%
CHI3L1
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	1	rs4950927 dbSNP Clinvar	203148633	2742.03	A	G	PASS	1/1	95	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.99960	0.99960	0.00185				None None	None None None None	CHI3L1\|0.048433283\|63.15%
CHI3L2
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	1	rs2494007 dbSNP Clinvar	111783996	1447.03	A	G	PASS	1/1	53	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.99940	0.99940	0.00062				None None	None None None None	CHI3L2\|0.012602272\|78.81%
CHIA
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	1	rs2275253 dbSNP Clinvar	111861841	3568.03	A	G	PASS	1/1	114	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.65915	0.65910	0.27764	0.99	0.00		None None	None None None None	CHIA\|0.03435619\|67.66%
CPOX
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	3	rs1729995 dbSNP Clinvar	98304467	1991.03	T	C	PASS	1/1	63	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.75399	0.75400	0.25611				None None	None None None None	CPOX\|0.108402411\|49.49%
DUSP12
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	1	rs1063178 dbSNP Clinvar	161721707	980.6	C	T	PASS	0/1	63	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.36002	0.36000	0.35399				None None	None None None None	DUSP12\|0.090238655\|53.19%
EPHA2
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	1	rs2230597 dbSNP Clinvar	16464673	5110.03	G	A	PASS	1/1	164	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.34944	0.34940	0.38879				None None	None None None None	EPHA2\|0.768915771\|6.62%
GALM
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	2	rs6741892 dbSNP Clinvar	38916970	521.6	A	T	PASS	0/1	40	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.18351	0.18350	0.13148	0.93	0.00		None None	None None None None	GALM\|0.264774088\|30.32%
HAAO
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	2	rs3816183 dbSNP Clinvar	43015719	1196.03	T	C	PASS	1/1	46	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.85963	0.85960	0.20637	1.00	0.00		None None	None None None None	HAAO\|0.143962065\|43.87%
HK2
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	2	rs10194657 dbSNP Clinvar	75115108	1375.6	A	G	PASS	0/1	90	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.52416	0.52420	0.42842				None None	None None None None	HK2\|0.435064932\|18.94%
HSPA6
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	1	rs1079109 dbSNP Clinvar	161495040	3778.03	C	T	PASS	1/1	129	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.12420	0.12420	0.08957	0.00	1.00		None None	None None None None	HSPA6\|0.031348421\|68.86%
IDH1
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	2	rs34218846 dbSNP Clinvar	209108317	709.6	C	T	PASS	0/1	51	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.04932	0.04932	0.06251	0.11	0.98		None None	None None None None	IDH1\|0.731476826\|7.62%
	View	wt108005 snp	2	rs11554137 dbSNP Clinvar	209113192	777.6	G	A	PASS	0/1	75	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.05691	0.05691	0.07104				None None	None None None None	IDH1\|0.731476826\|7.62%
IL22RA1
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	1	rs10903022 dbSNP Clinvar	24465113	2291.03	C	T	PASS	1/1	83	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.47065	0.47060	0.34430				None None	None None None None	IL22RA1\|0.007247763\|83.26%
JAK1
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	1	rs2230588 dbSNP Clinvar	65310489	1064.6	T	C	PASS	0/1	117	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.37260	0.37260	0.34920				None None	None None None None	JAK1\|0.528307667\|14.64%
LGALS8
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	1	rs1126407 dbSNP Clinvar	236700807	1338.03	T	A	PASS	1/1	46	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.49980	0.49980	0.38159	1.00	0.01		None None	None None None None	LGALS8\|0.03333972\|68.01%
	View	wt108005 snp	1	rs1041935 dbSNP Clinvar	236700857	1500.03	C	T	PASS	1/1	49	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.50000	0.50000	0.38167	0.00	0.01		None None	None None None None	LGALS8\|0.03333972\|68.01%
MINA
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	3	rs832079 dbSNP Clinvar	97673268	2163.03	A	C	PASS	1/1	77	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.99301	0.99300	0.00192				None None	None None None None	MINA\|0.716968741\|8.06%
NCF2
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	1	rs2274064 dbSNP Clinvar	183542387	917.6	T	C	PASS	0/1	95	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.49161	0.49160	0.43003	0.81	0.00		None None	None None None None	SMG7\|0.512183924\|15.29%,NCF2\|0.147913497\|43.31%
NEK2
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	1	rs701929 dbSNP Clinvar	211846876	3219.03	A	G	PASS	1/1	106	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.60304	0.60300	0.49854				None None	None None None None	NEK2\|0.323638729\|25.91%
NEU2
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	2	rs2233394 dbSNP Clinvar	233899377	4269.03	C	T	PASS	1/1	136	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.18770	0.18770	0.15528				None None	None None None None	NEU2\|0.005389797\|85.32%
	View	wt108005 snp	2	rs2233384 dbSNP Clinvar	233897414	2765.03	C	A	PASS	1/1	96	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.04752	0.04752	0.01676	0.63	0.00		None None	None None None None	NEU2\|0.005389797\|85.32%
NTRK1
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	1	rs6334 dbSNP Clinvar	156846233	1265.6	G	A	PASS	0/1	120	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.21286	0.21290	0.19360				None None	None None None None	NTRK1\|0.341411283\|24.74%
PADI2
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	1	rs3818032 dbSNP Clinvar	17402255	816.6	C	T	PASS	0/1	73	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.52596	0.52600	0.38490				None None	None None None None	PADI2\|0.185823973\|38.27%
PADI4
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	1	rs2240335 dbSNP Clinvar	17674537	1401.03	C	A	PASS	1/1	52	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.42133	0.42130	0.35837				None None	None None None None	PADI4\|0.011425361\|79.64%
	View	wt108005 snp	1	rs874881 dbSNP Clinvar	17660499	1217.03	G	C	PASS	1/1	42	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.52197	0.52200	0.47094	0.45	0.19		None None	None None None None	PADI4\|0.011425361\|79.64%
PCSK9
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	1	rs540796 dbSNP Clinvar	55524197	5647.03	A	G	PASS	1/1	186	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.86921	0.86920	0.18222				None None	None None None None	PCSK9\|0.022266519\|73.06%
PNPT1
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	2	rs2627765 dbSNP Clinvar	55883317	2087.03	G	T	PASS	1/1	67	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.35663	0.35660	0.48677				None None	None None None None	PNPT1\|0.558873\|13.4%
PPARG
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	3	rs3856806 dbSNP Clinvar	12475557	1495.6	C	T	PASS	0/1	143	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.12660	0.12660	0.10664				None None	None None None None	PPARG\|0.999715311\|0.28%
PPT1
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	1	rs1800205 dbSNP Clinvar	40557033	1105.6	A	G	PASS	0/1	81	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.07388	0.07388	0.03491	0.37	0.04		None None	None None None None	PPT1\|0.381012222\|21.97%
PRMT6
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	1	rs2232016 dbSNP Clinvar	107599918	1915.6	C	T	PASS	0/1	175	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.12520	0.12520	0.15494	0.01	0.30		None None	None None None None	PRMT6\|0.233305779\|33.07%
RBBP4
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	1	rs2762904 dbSNP Clinvar	33133968	2292.03	T	C	PASS	1/1	77	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.96785	0.96790	0.03014				None None	None None None None	RBBP4\|0.867298197\|4.31%
STK17B
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	2	rs10931726 dbSNP Clinvar	197021276	1377.6	T	C	PASS	0/1	110	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.47025	0.47020	0.45187				None None	None None None None	STK17B\|0.190903367\|37.72%
SULT1C3
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	2	rs2219078 dbSNP Clinvar	108875198	1581.03	G	A	PASS	1/1	58	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.34984	0.34980	0.22720	0.00	1.00		None None	None None None None	SULT1C3\|0.000995386\|95.48%
THEM5
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	1	rs6587625 dbSNP Clinvar	151820324	4760.03	T	C	PASS	1/1	162	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.77796	0.77800	0.17454	1.00	0.00		None None	None None None None	THEM5\|0.019802757\|74.29%
	View	wt108005 snp	1	rs370580520 dbSNP Clinvar	151820701	1044.6	C	T	PASS	0/1	83	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.00040	0.00040		0.01	0.99		None None	None None None None	THEM5\|0.019802757\|74.29%
TNFAIP6
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	2	rs1046668 dbSNP Clinvar	152226570	978.6	A	G	PASS	0/1	83	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.17712	0.17710	0.19137	0.87	0.00		None None	None None None None	TNFAIP6\|0.338115785\|24.96%
	View	wt108005 snp	2	rs75295519 dbSNP Clinvar	152235888	936.6	G	A	PASS	0/1	75	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.01997	0.01997	0.00131	0.01	0.97		None None	None None None None	TNFAIP6\|0.338115785\|24.96%
XDH
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	2	rs192453952 dbSNP Clinvar	31604589	1410.6	C	T	PASS	0/1	98	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.00080	0.00080		0.63	0.00		None None	None None None None	XDH\|0.142298525\|44.11%
XYLB
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	wt108005 snp	3	rs818850 dbSNP Clinvar	38401839	1726.03	T	C	PASS	1/1	68	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.96326	0.96330	0.03560				None None	None None None None	XYLB\|0.051125156\|62.31%
	View	wt108005 snp	3	rs843890 dbSNP Clinvar	38408361	1714.03	G	A	PASS	1/1	59	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.89776	0.89780	0.11802				None None	None None None None	XYLB\|0.051125156\|62.31%
	View	wt108005 snp	3	rs704943 dbSNP Clinvar	38406773	2422.03	G	T	PASS	1/1	88	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH		0.89657	0.89660	0.12171				None None	None None None None	XYLB\|0.051125156\|62.31%