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 CHR:

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EXCLUDE ALL VARIANTS PRESENT IN 1000GENOMES 		DBSNP FREQUENCY

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+ Genes 2

Genes:
MLH3, RAD51B,

+ Genes associated with diseases 1

Genes at Omim

MLH3,
MLH3 Colorectal cancer, hereditary nonpolyposis, type 7, 614385 (3)
Colorectal cancer, somatic, 114500 (3)
{Endometrial cancer, susceptibility to}, 608089 (3)

Genes at Clinical Genomics Database

MLH3,
MLH3 Colorectal cancer, hereditary nonpolyposis type 7
Endometrial carcinoma

Genes at HGMD

Summary

Number of Variants: 17
Number of Genes: 2

Export to: CSV
  • Page 1 of 1

MLH3
Omim - GeneCards - NCBI
Options Individual Chr
 RsId
 Pos
 Qual
 Ref
 Alt
 Filter Gen
 Read Depth Effect Impact Func Class 1kgenomes dbSNP ESP6500 Sift PP2 CADD M-CAP CLINVAR HI Score
View 16on271_ionxpress_012 14 rs28756992
dbSNP Clinvar 		75513826 451.935 T C PASS 0/1 282 NON_SYNONYMOUS_CODING MODERATE None 0.01697 0.01697 0.01530 0.31 0.00 None None None None None None MLH3|0.168045017|40.57%
View 16on271_ionxpress_012 14 rs175080
dbSNP Clinvar 		75513828 738.338 G A PASS 0/1 283 NON_SYNONYMOUS_CODING MODERATE None 0.36382 0.36380 0.44264 0.18 0.01 None None None None None None MLH3|0.168045017|40.57%
View 16on271_ionxpress_012 14 rs175081
dbSNP Clinvar 		75513883 2625.35 T C PASS 1/1 274 NON_SYNONYMOUS_CODING MODERATE None 0.99042 0.99040 0.01123 0.20 0.00 None None None None None None MLH3|0.168045017|40.57%
View 16on271_ionxpress_012 14 rs28756990
dbSNP Clinvar 		75514138 365.935 C A PASS 0/1 156 NON_SYNONYMOUS_CODING MODERATE None 0.00060 0.02596 0.02199 0.44 0.67 None None None None None None MLH3|0.168045017|40.57%
View 16on271_ionxpress_012 14 . 75514603 26.1955 C T PASS 0/1 116 NON_SYNONYMOUS_CODING MODERATE None 0.22 0.07 None None None None None None MLH3|0.168045017|40.57%
View 16on271_ionxpress_012 14 rs28756980
dbSNP Clinvar 		75515693 676.43 C T PASS 0/1 383 SYNONYMOUS_CODING LOW None 0.02596 0.02596 0.02076 None None None None None None MLH3|0.168045017|40.57%

RAD51B
Omim - GeneCards - NCBI
Options Individual Chr
 RsId
 Pos
 Qual
 Ref
 Alt
 Filter Gen
 Read Depth Effect Impact Func Class 1kgenomes dbSNP ESP6500 Sift PP2 CADD M-CAP CLINVAR HI Score
View 16on271_ionxpress_012 14 . 69061285 28.6435 CT C,CC PASS 0/1 49 None None None None None None None None None None
View 16on271_ionxpress_012 14 rs33929366
dbSNP Clinvar 		68353913 346.656 T G PASS 0/1 178 NON_SYNONYMOUS_CODING MODERATE None 0.00919 0.00919 0.00954 0.21 0.12 None None None None None None None
Omim - GeneCards - NCBI
Options Individual Chr
 RsId
 Pos
 Qual
 Ref
 Alt
 Filter Gen
 Read Depth Effect Impact Func Class 1kgenomes dbSNP ESP6500 Sift PP2 CADD M-CAP CLINVAR HI Score
View 16on271_ionxpress_012 14 rs1474939
dbSNP Clinvar 		68331675 136.307 A T PASS 1/1 15 None None None None None None None None None None
View 16on271_ionxpress_012 14 rs1778057
dbSNP Clinvar 		95566108 31.4308 C A PASS 0/1 42 None None None 0.87001 0.87000 None None None None None None DICER1|0.959525811|1.99%
View 16on271_ionxpress_012 14 rs115390593
dbSNP Clinvar 		69061033 155.522 C T PASS 0/1 50 None None None 0.01118 0.01118 None None None None None None None
View 16on271_ionxpress_012 14 rs77157930
dbSNP Clinvar 		75485519 234.569 G C PASS 0/1 109 None None None 0.02536 0.02536 0.02015 None None None None None None MLH3|0.168045017|40.57%
View 16on271_ionxpress_012 14 rs175056
dbSNP Clinvar 		75489446 1866.9 T C PASS 1/1 195 None None None 0.99042 0.99040 None None None None None None MLH3|0.168045017|40.57%
View 16on271_ionxpress_012 14 rs175057
dbSNP Clinvar 		75489632 3058.41 C T PASS 1/1 318 None None None 0.40635 0.40630 0.48362 None None None None None None MLH3|0.168045017|40.57%
View 16on271_ionxpress_012 14 rs75767827
dbSNP Clinvar 		75500042 176.438 T C PASS 0/1 81 None None None 0.01438 0.01438 None None None None None None MLH3|0.168045017|40.57%
View 16on271_ionxpress_012 14 rs175075
dbSNP Clinvar 		75505016 953.284 A G PASS 1/1 99 None None None 0.98622 0.98620 0.01553 None None None None None None MLH3|0.168045017|40.57%
View 16on271_ionxpress_012 14 rs13078
dbSNP Clinvar 		95556747 172.967 A T PASS 0/1 82 None None None 0.90895 0.90890 None None None None None None DICER1|0.959525811|1.99%
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