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VARIANT EFFECT	FUNCTIONAL CLASS	IMPACT
MUTATION TYPE:	CHR: POS:

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SHOW ONLY VARIANTS PRESENT IN COMMON GENES BETWEEN ALL THE INDIVIDUALS SELECTED SHOW ONLY VARIANTS AT EXACTLY SAME POSITION BETWEEN ALL THE INDIVIDUALS SELECTED EXCLUDE ALL VARIANTS PRESENT IN LATEST DBSNP BUILD SHOW ONLY VARIANTS PRESENT AT HGMD

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Genes:
ACACB, ACLY, ACSM2A, ADCK3, AKT1, ALDH4A1, CLIC4, COMT, CPOX, CYP11B2, DHRS4, ECHDC3, FASN, HK2, HSPA9, IDE, KYNU, NLRX1, NME3, OAT, PARP1, PCK1, PDK2, PNPT1, POLRMT, PTGR2, RTN4IP1, SIRT5, SND1, THEM5, TPH2, TRAP1, ZADH2,

+ Genes associated with diseases 13

Genes at Omim

ADCK3, AKT1, ALDH4A1, COMT, CPOX, CYP11B2, HSPA9, KYNU, OAT, PCK1, PNPT1, RTN4IP1, TPH2,

ADCK3	Coenzyme Q10 deficiency, primary, 4, 612016 (3)
AKT1	Breast cancer, somatic, 114480 (3) Colorectal cancer, somatic, 114500 (3) Cowden syndrome 6, 615109 (3) {Schizophrenia, susceptibility to}, 181500 (2) Ovarian cancer, somatic, 167000 (3) Proteus syndrome, somatic, 176920 (3)
ALDH4A1	Hyperprolinemia, type II, 239510 (3)
COMT	{Panic disorder, susceptibility to}, 167870 (3) {Schizophrenia, susceptibility to}, 181500 (3)
CPOX	Coproporphyria, 121300 (3) Harderoporphyria, 121300 (3)
CYP11B2	Aldosterone to renin ratio raised (3) {Low renin hypertension, susceptibility to} (3) Hypoaldosteronism, congenital, due to CMO I deficiency, 203400 (3) Hypoaldosteronism, congenital, due to CMO II deficiency, 610600 (3)
HSPA9	Anemia, sideroblastic, 4, 182170 (3) Even-plus syndrome, 616854 (3)
KYNU	Vertebral, cardiac, renal, and limb defects syndrome 2, 617661 (3) ?Hydroxykynureninuria, 236800 (3)
OAT	Gyrate atrophy of choroid and retina with or without ornithinemia, 258870 (3)
PCK1	?Phosphoenolpyruvate carboxykinase deficiency, cytosolic, 261680 (3)
PNPT1	Combined oxidative phosphorylation deficiency 13, 614932 (3) Deafness, autosomal recessive 70, 614934 (3)
RTN4IP1	Optic atrophy 10 with or without ataxia, mental retardation, and seizures, 616732 (3)
TPH2	{Unipolar depression, susceptibility to}, 608516 (3) {Attention deficit-hyperactivity disorder, susceptibility to, 7}, 613003 (3)

Genes at Clinical Genomics Database

ADCK3, AKT1, ALDH4A1, COMT, CPOX, CYP11B2, HSPA9, KYNU, OAT, PNPT1, RTN4IP1, TRAP1,

ADCK3	Coenzyme Q10 deficiency Progressive cerebellar ataxia and atrophy Spinocerebellar ataxia 9
AKT1	Cowden syndrome 6 Proteus syndrome
ALDH4A1	Hyperprolinemia, type II
COMT	Medication response, association with
CPOX	Coproporphyria Harderoporphyria
CYP11B2	Corticosterone methyloxidase type I deficiency Corticosterone methyloxidase type II deficiency Glucocorticoid-remediable aldosteronism
HSPA9	Anemia, sideroblastic 4
KYNU	Hydroxykynureninuria
OAT	Gyrate atrophy of choroid and retina
PNPT1	Deafness, autosomal recessive 70
RTN4IP1	Optic atrophy 10 with or without ataxia, mental retardation, and seizures
TRAP1	Congenital abnormalities of the kidney and urinary tract VACTERL association

Genes at HGMD

Summary

Number of Variants: 38
Number of Genes: 33

Export to: CSV

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ACACB
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	gpp10315_20120828021333_nucseek	12	rs11065772 dbSNP Clinvar	109617865	16713.01	T	C	PASS	1/1	486	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH	None	0.67732	0.67730	0.25996				None None	None None None None	ACACB\|0.108212697\|49.54%
ACLY
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	gpp10315_20120828021333_nucseek	17	rs8065502 dbSNP Clinvar	40048613	32767.01	A	G	PASS	1/1	2250	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH	None	0.90435	0.90440	0.12479				None None	None None None None	ACLY\|0.44685425\|18.3%
ACSM2A
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	gpp10315_20120828021333_nucseek	16	rs1700805 dbSNP Clinvar	20488696	88.01	A	G	PASS	0/1	22	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH	None	0.48482	0.48480	0.35969				None None	None None None None	ACSM2A\|0.005190474\|85.6%
ADCK3
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	gpp10315_20120828021333_nucseek	1	rs3738725 dbSNP Clinvar	227174210	32767.01	T	C	PASS	1/1	2276	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH	None	0.31390	0.31390	0.44218				None None	None None None None	ADCK3\|0.102470418\|50.69%
AKT1
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	gpp10315_20120828021333_nucseek	14	rs139297659 dbSNP Clinvar	105238711	7693.01	G	A	PASS	0/1	701	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH	None	0.00899	0.00899	0.00953				None None	None None None None	AKT1\|0.999993361\|0.05%
ALDH4A1
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	gpp10315_20120828021333_nucseek	1	rs2230705 dbSNP Clinvar	19203997	8815.01	C	G	PASS	0/1	853	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH	None	0.64157	0.64160	0.28846				None None	None None None None	ALDH4A1\|0.121498662\|47.22%
	View	gpp10315_20120828021333_nucseek	1	rs2230708 dbSNP Clinvar	19201956	5634.01	A	G	PASS	1/1	139	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH	None	0.73722	0.73720	0.29779				None None	None None None None	ALDH4A1\|0.121498662\|47.22%
	View	gpp10315_20120828021333_nucseek	1	rs7550938 dbSNP Clinvar	19202917	23428.01	T	C	PASS	1/1	756	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH	None	0.66094	0.66090	0.37698				None None	None None None None	ALDH4A1\|0.121498662\|47.22%
CLIC4
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	gpp10315_20120828021333_nucseek	1	.	25167420	6777.01	A	G	PASS	0/1	541	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH	None				0.28	0.00		None None	None None None None	CLIC4\|0.511630101\|15.31%
COMT
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	gpp10315_20120828021333_nucseek	22	rs4818 dbSNP Clinvar	19951207	14883.01	C	G	PASS	0/1	1321	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH	None	0.29693	0.29690	0.32754				None None	None None None None	COMT\|0.166055932\|40.8%
	View	gpp10315_20120828021333_nucseek	22	rs4680 dbSNP Clinvar	19951271	8242.01	G	A	PASS	0/1	797	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH	None	0.36921	0.36920	0.45148	0.09	0.22		None None	None None None None	COMT\|0.166055932\|40.8%
	View	gpp10315_20120828021333_nucseek	22	rs4633 dbSNP Clinvar	19950235	2159.01	C	T	PASS	0/1	283	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH	None	0.37161	0.37160	0.46009				None None	None None None None	COMT\|0.166055932\|40.8%
CPOX
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	gpp10315_20120828021333_nucseek	3	rs1729995 dbSNP Clinvar	98304467	2643.01	T	C	PASS	0/1	131	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH	None	0.75399	0.75400	0.25611				None None	None None None None	CPOX\|0.108402411\|49.49%
CYP11B2
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	gpp10315_20120828021333_nucseek	8	rs4538 dbSNP Clinvar	143994702	5596.01	G	T	PASS	0/1	654	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH	None	0.60763	0.60760	0.46585				None None	None None None None	GML\|0.000127964\|99.9%,CYP11B2\|0.013075672\|78.46%
DHRS4
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	gpp10315_20120828021333_nucseek	14	rs765273457 dbSNP Clinvar	24438063	80.26	A	C	PASS	1/1	199	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH	None				0.19	0.74		None None	None None None None	DHRS4\|0.01129792\|79.79%
ECHDC3
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	gpp10315_20120828021333_nucseek	10	rs10906011 dbSNP Clinvar	11805357	32767.01	G	A	PASS	1/1	1778	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH	None	0.51578	0.51580	0.45548				None None	None None None None	ECHDC3\|0.029496468\|69.61%
	View	gpp10315_20120828021333_nucseek	10	rs7899215 dbSNP Clinvar	11797436	21147.01	T	C	PASS	1/1	759	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH	None	0.93131	0.93130	0.06366				None None	None None None None	ECHDC3\|0.029496468\|69.61%
FASN
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	gpp10315_20120828021333_nucseek	17	rs2228309 dbSNP Clinvar	80051183	16428.01	A	G	PASS	1/1	732	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH	None	0.39177	0.39180	0.45840				None None	None None None None	FASN\|0.307148829\|27.07%
HK2
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	gpp10315_20120828021333_nucseek	2	rs10194657 dbSNP Clinvar	75115108	14589.01	A	G	PASS	0/1	1674	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH	None	0.52416	0.52420	0.42842				None None	None None None None	HK2\|0.435064932\|18.94%
HSPA9
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	gpp10315_20120828021333_nucseek	5	rs1042665 dbSNP Clinvar	137902339	9528.01	T	C	PASS	0/1	852	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH	None	0.41993	0.41990	0.25350				None None	None None None None	HSPA9\|0.978462379\|1.51%
IDE
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	gpp10315_20120828021333_nucseek	10	rs35426658 dbSNP Clinvar	94246992	5586.01	C	A	PASS	0/1	400	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH	None	0.02117	0.02117	0.01346				None None	None None None None	IDE\|0.983146007\|1.37%
KYNU
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	gpp10315_20120828021333_nucseek	2	rs9013 dbSNP Clinvar	143798189	16681.01	A	G	PASS	0/1	1471	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH	None	0.17572	0.17570	0.16108	0.38	0.00		None None	None None None None	KYNU\|0.158092814\|41.86%
NLRX1
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	gpp10315_20120828021333_nucseek	11	rs4245191 dbSNP Clinvar	119052826	7512.01	C	A	PASS	0/1	714	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH	None	0.68830	0.68830	0.42664	1.00	0.84		None None	None None None None	NLRX1\|0.100054639\|51.16%
NME3
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	gpp10315_20120828021333_nucseek	16	rs11890 dbSNP Clinvar	1820992	18061.01	T	A	PASS	1/1	671	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH	None	0.76358	0.76360	0.16050				None None	None None None None	NME3\|0.015536375\|76.78%
OAT
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	gpp10315_20120828021333_nucseek	10	rs11461 dbSNP Clinvar	126089434	8278.01	G	A	PASS	1/1	370	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH	None	0.40994	0.40990	0.31526				None None	None None None None	OAT\|0.248692734\|31.64%
PARP1
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	gpp10315_20120828021333_nucseek	1	rs1805404 dbSNP Clinvar	226589958	7751.01	G	A	PASS	0/1	832	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH	None	0.21825	0.21830	0.14770				None None	None None None None	PARP1\|0.909670584\|3.25%
PCK1
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	gpp10315_20120828021333_nucseek	20	rs1062600 dbSNP Clinvar	56137798	32767.01	G	A	PASS	1/1	1622	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH	None	0.29513	0.29510	0.41273				None None	None None None None	PCK1\|0.222187603\|34.18%
PDK2
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	gpp10315_20120828021333_nucseek	17	rs9839 dbSNP Clinvar	48174908	9302.01	C	T	PASS	0/1	714	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH	None	0.43510	0.43510	0.35553				None None	None None None None	PDK2\|0.36750575\|22.9%
PNPT1
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	gpp10315_20120828021333_nucseek	2	rs2627765 dbSNP Clinvar	55883317	5767.01	G	T	PASS	0/1	534	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH	None	0.35663	0.35660	0.48677				None None	None None None None	PNPT1\|0.558873\|13.4%
POLRMT
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	gpp10315_20120828021333_nucseek	19	.	621205	1168.01	G	A	PASS	0/1	130	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH	None							None None	None None None None	None
PTGR2
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	gpp10315_20120828021333_nucseek	14	rs11159042 dbSNP Clinvar	74340797	8303.01	A	T	PASS	1/1	225	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH	None	0.50499	0.50500	0.47232				None None	None None None None	PTGR2\|0.202949681\|36.39%
RTN4IP1
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	gpp10315_20120828021333_nucseek	6	rs9486410 dbSNP Clinvar	107019880	2882.01	A	G	PASS	0/1	197	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH	None	0.18550	0.18550	0.16985				None None	None None None None	RTN4IP1\|0.197541433\|36.99%
SIRT5
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	gpp10315_20120828021333_nucseek	6	rs3757261 dbSNP Clinvar	13599303	15476.01	C	T	PASS	0/1	1504	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH	None	0.17173	0.17170	0.17753				None None	None None None None	SIRT5\|0.137206779\|44.83%
SND1
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	gpp10315_20120828021333_nucseek	7	rs322825 dbSNP Clinvar	127721507	17306.01	T	C	PASS	0/1	1758	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH	None	0.67252	0.67250	0.24927				None None	None None None None	SND1\|0.892258294\|3.61%
THEM5
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	gpp10315_20120828021333_nucseek	1	rs6587625 dbSNP Clinvar	151820324	21240.01	T	C	PASS	0/1	2165	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH	None	0.77796	0.77800	0.17454	1.00	0.00		None None	None None None None	THEM5\|0.019802757\|74.29%
TPH2
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	gpp10315_20120828021333_nucseek	12	rs4290270 dbSNP Clinvar	72416235	13975.01	A	T	PASS	1/1	555	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH	None	0.48722	0.48720	0.43380				None None	None None None None	TPH2\|0.532472095\|14.47%
TRAP1
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	gpp10315_20120828021333_nucseek	16	rs1136948 dbSNP Clinvar	3721773	10174.01	G	C	PASS	0/1	957	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH	None	0.10823	0.10820	0.13422	0.00	1.00		None None	None None None None	DNASE1\|0.039855019\|65.82%,TRAP1\|0.168599632\|40.51%
ZADH2
Omim - GeneCards - NCBI
	Options	Individual	Chr	RsId	Pos	Qual	Ref	Alt	Filter	Gen	Read Depth	Effect	Impact	Func Class	1kgenomes	dbSNP	ESP6500	Sift	PP2	CADD	M-CAP	CLINVAR	HI Score
	View	gpp10315_20120828021333_nucseek	18	rs7230037 dbSNP Clinvar	72914280	15867.01	G	A	PASS	1/1	705	PROTEIN_STRUCTURAL_INTERACTION_LOCUS	HIGH	None	0.29752	0.29750	0.31324				None None	None None None None	ZADH2\|0.048701757\|63.04%